1.Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.
结论慢性间断性低氧能明显增加大鼠肝脏erd (CYP3A2)和ANH (CYP2E1)活性，其机制可能与其在转录水平上提高肝脏cyp3a2和CYP2E1的基因表达水平有关。
2.Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.
结论慢性间断性低氧能明显增加大鼠肝脏erd (CYP3A2)和ANH (CYP2E1)活性，其机制可能与其在转录水平上提高肝脏cyp3a2和CYP2E1的基因表达水平有关。
3.Hypoxia inducible factor-l (HIF-1), which can stimulate expression of hypoxia induced-responsed, is a kind of transcriptive factor.
缺氧诱导因子- 1 (HIF - 1)是由低氧等诱导细胞产生的1种转录因子，能激活许多缺氧反应性基因的表达。